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Management of Multiple Drug-Resistant Infections
  • Author : Stephen H. Gillespie
  • Publisher : Springer Science & Business Media
  • Release Date : 2004-01-12
  • Category: Medical
  • Pages : 403
  • ISBN Code: 1592597386

Summary: A comprehensive and cutting-edge review of how practicing physicians can best treat multiple drug resistance in bacterial, viral, protozoal, and helminthic infections. The authors focus on the major hospital and community-acquired pathogens, including S. aureus, S. pneumoniae, Enterococcus, Acinetobacter, and M. tuberculosis, and on the management of such common problems as multiple drug-resistant urinary tract infections and gonorrhea. Among the resistant tropical organisms covered are Salmonella typhi, malaria, and Burkholderia pseudomalei. Resistance to such important antiviral classes as antiretrovirals and anticytomegalovirals is also discussed, as are those measures necessary to prevent the spread of infections patients.

Infection Control
  • Author : Silpi Basak
  • Publisher : BoD – Books on Demand
  • Release Date : 2013-05-29
  • Category: Medical
  • Pages : 102
  • ISBN Code: 9535111450

Summary: Health Care associated infection (HAI) is an emerging problem worldwide. HAI causes increased morbidity, mortality and average length of stay of the patient in the hospital. HAI also imposes economic burden on the patient, health care set up and also State and National Health care system. It has been estimated that 5 10 % of all hospital admission suffers from HAI even in developed countries. But 30% of HAI are preventable, if we follow the infection control practices properly especially hand hygiene while giving patient care. Hence, in this book importance has been given to Infection Control practices along with emerging trends of HAI due to Pseudomonas aeruginosa, Acinetobacter species etc.

Guidelines for the Programmatic Management of Drug-resistant Tuberculosis
  • Author : World Health Organization
  • Publisher : World Health Organization
  • Release Date : 2008
  • Category: Medical
  • Pages : 247
  • ISBN Code: 9241547588

Summary: The emergence of extensively drug-resistant strains of tuberculosis, especially in countries with a high prevalence of human immunodeficiency virus, is a serious threat to global public health and jeopardizes efforts to effectively control the disease. This publication offers updated recommendations for the diagnosis and management of drug-resistant tuberculosis in a variety of geographical, economic and social settings, and the recording of data that enables the monitoring and evaluation of programs.--Publisher's description.

Antimicrobial Resistance in Developing Countries
  • Author : Aníbal de J. Sosa,Denis K. Byarugaba,Carlos F. Amábile-Cuevas,Po-Ren Hsueh,Samuel Kariuki,Iruka N. Okeke
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-10-08
  • Category: Science
  • Pages : 554
  • ISBN Code: 9780387893709

Summary: Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and crops from a short growing season. Waterborne infections were averted by owning your own well or supporting a community reservoir. Everyone got vaccines in rich countries, while people in others got them later if at all. Antimicrobial agents seemed at first to be an exception. They did not need to be delivered through a cold chain and to everyone, as vaccines did. They had to be given only to infected patients and often then as relatively cheap injectables or pills off a shelf for only a few days to get astonishing cures. Antimicrobials not only were better than most other innovations but also reached more of the world’s people sooner. The problem appeared later. After each new antimicrobial became widely used, genes expressing resistance to it began to emerge and spread through bacterial populations. Patients infected with bacteria expressing such resistance genes then failed treatment and remained infected or died. Growing resistance to antimicrobial agents began to take away more and more of the cures that the agents had brought.

Antimicrobial Resistance
  • Author : J.T. Weber
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2010-03-17
  • Category: Medical
  • Pages : 184
  • ISBN Code: 3805593244

Summary: Preventing, controlling and treating drug-resistant infections is one of the major challenges in modern medicine. Antimicrobial Resistance goes beyond simple definitions and microbiological data to fully explore this rapidly changing area, describing evidence for effective interventions, costs, treatment strategies and directions for future research.Each chapter provides essential background and examines the evidence for an important aspect of prevention and control, treatment strategy or policy decision. Prevention and control strategies are analyzed for inappropriate antimicrobial use, fluoroquinolone-resistant organisms, health-care associated infections and parasitic diseases. Furthermore, treatment strategies for changing resistance patterns are explored for community-acquired pneumonia during an influenza pandemic and infections with community-associated MRSA, extended-spectrum beta-lactamase producing organisms and fungi. Data for policy making are presented in articles that detail the costs of antimicrobial-resistant infections in healthcare settings and the threat of resistance with the introduction of antiretroviral therapy for large populations in the developing world. These reviews show where interventions, surveillance and research will be most useful in the future. Antimicrobial Resistance is an invaluable contribution for infectious disease physicians and public health officials who are interested in the prevention of antimicrobial-resistant infections.

Pulmonary Infections, An Issue of Sleep Medicine Clinics - E-Book
  • Author : Michael Niederman
  • Publisher : Elsevier Health Sciences
  • Release Date : 2011-09-23
  • Category: Medical
  • Pages : 205
  • ISBN Code: 1455711985

Summary: This issue provides fully updated information on respiratory infections, including healthcare associated pneumonia, new diagnostic tests for pneumonia, epidemic viral pneumonia and other emerging pathogens, biomarkers to optimize antibiotic therapy for pneumonia, pharmacokinetics and pharmacodynamics to improve management of penumonia. Nosocomial tracheobronchitis and bronchiectasis are also discussed. Articles on CAP and VAP, including an examination of the impact of guidelines on outcomes, de-escalation therapy, inhaled antibiotic therapy and prevention of VAP are also included.

Antiseptic Stewardship
  • Author : Günter Kampf
  • Publisher : Springer
  • Release Date : 2018-08-25
  • Category: Medical
  • Pages : 694
  • ISBN Code: 3319987852

Summary: Various antiseptic agents, such as chlorhexidine, are used for different applications, e.g. in healthcare, veterinary medicine, animal production and household products, including cosmetics. However, not all antiseptic agents provide significant health benefits, especially in some products used in human medicine (alcohol-based hand rubs, antimicrobial soaps). While some products (antimicrobial soaps, surface disinfectants, instrument disinfectants, wound antiseptics) may contain one or more biocidal agents with a comparable antimicrobial efficacy but large differences in their potential for microbial adaptation and tolerance. An increased bacterial resistance has been described for various antimicrobial agents, sometimes including a cross-resistance to antibiotics. The book is the first comprehensive reference resource on antiseptic agents, including their efficacy, natural and acquired resistance, adaptation, and cross-resistance. It also discusses their and appropriate use in terms of a balance between their efficacy and the risk of acquired bacterial resistance / tolerance. Focusing on human and veterinary medicine and household products, it helps readers make informed decisions concerning against antiseptic products based on their composition. The book contributes to reduce any unnecessary selection pressure towards emerging pathogens and to keep the powerful antiseptic agents for all those applications that have a clear benefit (e.g. reduction of healthcare-associated infection).

The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes
  • Author : Leslie L. Barton,Neil R. Friedman
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-04-25
  • Category: Medical
  • Pages : 421
  • ISBN Code: 9781597453912

Summary: In this concise book, an international panel of experts provide a succinct, up-to-date, evidence-based reference to the neurological consequences of infectious diseases and immunodeficiency syndromes in children in one readily accessible volume. Within each of its conveniently structured chapters, readers will find a general description of the disease or disorder. Finally a volume for pediatricians, neurologists, infectious disease specialists and all who care for children.

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
  • Author : Mahendra Rai,Kateryna Kon
  • Publisher : Academic Press
  • Release Date : 2013-05-24
  • Category: Medical
  • Pages : 296
  • ISBN Code: 0124017088

Summary: Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells and more

Guidelines for the Programmatic Management of Drug-resistant Tuberculosis
  • Author : World Health Organization
  • Publisher : World Health Organization
  • Release Date : 2008
  • Category: Medical
  • Pages : 247
  • ISBN Code: 9241547588

Summary: The emergence of extensively drug-resistant strains of tuberculosis, especially in countries with a high prevalence of human immunodeficiency virus, is a serious threat to global public health and jeopardizes efforts to effectively control the disease. This publication offers updated recommendations for the diagnosis and management of drug-resistant tuberculosis in a variety of geographical, economic and social settings, and the recording of data that enables the monitoring and evaluation of programs.--Publisher's description.

Antibiotic Resistance
  • Author : Kateryna Kon,Mahendra Rai
  • Publisher : Academic Press
  • Release Date : 2016-06-14
  • Category: Medical
  • Pages : 436
  • ISBN Code: 0128036680

Summary: Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches discusses up-to-date knowledge in mechanisms of antibiotic resistance and all recent advances in fighting microbial resistance such as the applications of nanotechnology, plant products, bacteriophages, marine products, algae, insect-derived products, and other alternative methods that can be applied to fight bacterial infections. Understanding fundamental mechanisms of antibiotic resistance is a key step in the discovery of effective methods to cope with resistance. This book also discusses methods used to fight antibiotic-resistant infection based on a deep understanding of the mechanisms involved in the development of the resistance. Discusses methods used to fight antibiotic-resistant infection based on a deep understanding of mechanisms involved in the development of the resistance Provides information on modern methods used to fight antibiotic resistance Covers a wide range of alternative methods to fight bacterial resistance, offering the most complete information available Discusses both newly emerging trends and traditionally applied methods to fight antibiotic resistant infections in light of recent scientific developments Offers the most up-to-date information in fighting antibiotic resistance Includes involvement of contributors all across the world, presenting questions of interest to readers of both developed and developing countries

Advances in HIV and AIDS Control
  • Author : Samuel Ikwaras Okware
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-12-12
  • Category: Medical
  • Pages : 258
  • ISBN Code: 1789846021

Summary: The HIV epidemic has had a significant and profound impact on the world and health resources. Considerable progress has been made in understanding the risks and drivers of the epidemic. Antiretroviral drugs have relieved human suffering and prolonged life. However, access to quality management needs to scale up and be made universal. This book discusses critical issues related to the treatment of HIV infection and related co-infections and challenges in adherence and discordancy. New vaccine approaches discussed may provide the ultimate solution for eradication. Sharing knowledge from various experts in medical and basic sciences improves the quality of care for this persistent global threat. This book discusses emerging advances in HIV-AIDS management to support strategies for control and elimination.

Contemporary Topics of Pneumonia
  • Author : Zissis Chroneos
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-12-20
  • Category: Medical
  • Pages : 222
  • ISBN Code: 9535137077

Summary: Pneumonia is an inflammatory disease of the air sacs and surrounding interstitium caused by infectious agents or by endogenous inflammatory tissue disorder termed interstitial pneumonia. The present book covers contemporary topics of community, hospital, and health care-related bacterial and viral pneumonia in the setting of drug resistance, environmental exposures, climate change, hormonal influences, and gender. The topic of interstitial pneumonia is brought under the lens of an immune-related connective tissue disease.

ASM News
  • Author : N.A
  • Publisher : Unknown
  • Release Date : 2004
  • Category: Microbiology
  • Pages : N.A
  • ISBN Code: N.A


Management of Antimicrobials in Infectious Diseases
  • Author : Arch G. Mainous III,Claire Pomeroy
  • Publisher : Springer Science & Business Media
  • Release Date : 2000-08-29
  • Category: Medical
  • Pages : 350
  • ISBN Code: 1592590365

Summary: Arch Mainous III, PhD, Claire Pomeroy, MD, and a panel of experienced physicians offer an eminently practical summary of the most effective evidence-based antimicrobial treatments encountered in both hospital and outpatient settings. Focusing on the clinical impact of appropriate diagnosis and treatment, the book emphasizes those newer aspects of infectious disease management necessitated by the growing problem of antibiotic resistance. It also discusses the major pathogens involved so that practicing clinicians will not only diagnose, but also better treat the infections and complications they cause. Multidisciplinary and highly practical, Management of Antimicrobials in Infectious Diseases: Impact of Antibiotic Resistance offers busy clinicians and nurse practitioners a comprehensive and informed guide to navigating the difficult treatment decisions created by the rising tide of antibiotic resistance today.

Escherichia coli
  • Author : Amidou Samie
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-07-12
  • Category: Medical
  • Pages : 434
  • ISBN Code: 9535133292

Summary: Escherichia coli is a versatile organism and very diverse. Members of this species vary from very pathogenic agents causing different types of diseases including meningitis, gastroenteritis, and septicemia, just to cite a few, to harmless organisms living in the intestines of both humans and animals. E. coli has also been used as a model organism for most bacteria except a few. For this reason, its study provides a huge advantage and can help understand the mechanisms involved in different processes such as pathogenesis, environmental disinfection, nutrient utilization, antibiotic resistance, and diagnostic/detection methods, and these are indeed the topics discussed in this book. The book has been divided into four main sections representing the different facets of E. coli applications, which include disease, biotechnology, environmental engineering and innovative approaches to detection, and lastly its physiology and cell biology. Such processes can be applied to the study of other organisms as well considering the development of diversity; for example, many organisms are capable of horizontal gene transfer, which is capable of increasing the fitness of the bacterial organisms involved and has a great impact on the control of such bacterial organism.

Challenges to Tackling Antimicrobial Resistance
  • Author : Michael Anderson,Michele Cecchini,Elias Mossialos
  • Publisher : Cambridge University Press
  • Release Date : 2020-04-30
  • Category: Health & Fitness
  • Pages : 240
  • ISBN Code: 1108799450

Summary: An accessible overview of the challenges in tackling AMR and the economic and policy responses of the 'One Health' approach. It will appeal to policy-makers seeking to strengthen national and local polices tackling AMR, as well as students and academics who want an overview of the latest scientific evidence regarding effective AMR policies.

Management of Peri-operative Complications, An Issue of Surgical Clinics - E-Book
  • Author : Stanley H. Rosenbaum,Lewis J. Kaplan
  • Publisher : Elsevier Health Sciences
  • Release Date : 2012-04-28
  • Category: Medical
  • Pages : 300
  • ISBN Code: 1455744395

Summary: Management of Peri-operative Complications is examined in the issue of Surgical Clinics, guest edited Drs. Lewis Kaplan and Stanley Rosenbaum. Topics include: fluids and electrolytes, hypoperfusion, shock states and ACS, surgical prophylaxis and complication avoidance bundles, NSQIP, SCIP and TQIP, post-operative malnutrition and probiotic therapy, post-operative malnutrition and probiotic therapy, damage control for intra-abdominal sepsis, multi-drug resistant organisms and antibiotic management, pneumonia and acute pulmonary failure, organ failure avoidance and mitigation strategies, delirium, EtOH withdrawal and polypharmacy withdrawal states, cellular and molecular physiology of nerve injury and persistent post-operative pain, acute pain management following operation: preventing chronic post-operative pain, massive transfusion and related issues, post-op ileus, SBO and colonic dysmotility, GI hemorrhage, and in-hospital rescue therapies.

Surgical Complications, An Issue of Veterinary Clinics: Small Animal Practice
  • Author : Christopher A. Adin
  • Publisher : Elsevier Health Sciences
  • Release Date : 2011-10-03
  • Category: Medical
  • Pages : 235
  • ISBN Code: 1455712116

Summary: A comprehensive review of small animal surgical complications for the general veterinary practitioner! Topics on complications will include: upper urinary tract surgery, lower urinary tract surgery, GI surgery, hepato-biliary surgery, spay/neuter surgery, reconstructive surgery, thoracic surgery, airway surgery, minimally invasive surgery, metabolic complications of endocrine surgery, ear surgery, surgical site infections, and more!

Dental Management of the Medically Compromised Patient - E-Book
  • Author : James W. Little,Donald Falace,Craig Miller,Nelson L. Rhodus
  • Publisher : Elsevier Health Sciences
  • Release Date : 2012-02-23
  • Category: Medical
  • Pages : 736
  • ISBN Code: 0323088015

Summary: Learn how common medical conditions can affect the course of the dental treatment a patient receives. This updated, concise reference provides the information you need to provide appropriate dental care to any patient, regardless of existing medical conditions. Featuring vivid illustrations and well-organized tables in each chapter, this text gives you the in-depth details and the overall summaries you need to get to the root of your patients’ needs. Organization of medical conditions provides a brief overview of the basic disease process, epidemiology, pathophysiology, signs and symptoms, laboratory findings, and currently accepted medical therapy of each disorder. This is followed by a detailed explanation and recommendations for specific dental management. Coverage of dosages, side effects, and drug interactions with medications used in dentistry, including those used during pregnancy. Chapters focusing on major health problems in the US and other nations include, ischemic hearth disease, smoking and tobacco use cessation, sleep-related breathing disorders, sexually transmitted diseases, diabetes mellitus, and psychiatric disorders. Dental management summary table summarizes important factors for consideration in the dental management of medically compromised patients. Appendix on the therapeutic management of common oral lesions provides a quick reference to the causative factors, clinical description, currently accepted therapeutic management, and patient education regarding common oral conditions. Appendix on alternative and complementary drugs looks at herbal remedies, specifically efficacy, adverse effects/reactions, medical problems, drug interactions, and dental implications. NEW! Chapter on drug and alcohol abuse discusses the effects of marijuana, cocaine, amphetamines/methamphetamine, and alcohol, along with considerations for both medical and dental management. NEW! 2009 AAOS statement on Antibiotic Prophylaxis for Bacteremia in Patients with Joint Replacements provides recommendations to supplement practitioners in their clinical judgment regarding antibiotic prophylaxis for patients with a joint prosthesis.

Management of Burns, An Issue of Surgical Clinics,
  • Author : Robert Sheridan
  • Publisher : Elsevier Health Sciences
  • Release Date : 2014-08-12
  • Category: Medical
  • Pages : 241
  • ISBN Code: 0323320449

Summary: Editor Robert Sheridan and authors review the latest in Management of Burns. Articles will include Reflection: evolution of the field over 50 years, Acute burn procedures and operations, Special injuries and illnesses, Initial evaluation and fluid resuscitation, Critical care of burns, Biology and principles of scar management and burn reconstruction, Management of common post-burn deformities, Burn recovery—physical and emotional rehabilitation, Anesthesia and pain control for burns, Outpatient burn management, Measuring burn outcomes, Burn care in disasters and austere settings, On the horizon--research priorities for the next decade, and more!

Update in the Medical Management of the Long Term Care Patient, An Issue of Clinics in Geriatric Medicine - E-Book
  • Author : Miguel A. Paniagua
  • Publisher : Elsevier Health Sciences
  • Release Date : 2011-07-22
  • Category: Medical
  • Pages : 240
  • ISBN Code: 1455712450

Summary: This issue brings the geriatrician up to date on topics in Longer-Term-Care such as: Doing Dementia Better: Anthropological Insights, Update on teaching in the Long-Term Care Setting, Pneumonia in the Long-Term Resident, Palliative Care for Patients with Dementia in Long Term Care, Urinary Tract Infections in Long-Term Care Residents, and Nausea and Other Non-Pain Symptoms in Long-term Care.

Infection Prevention and Control in the Hospital, An Issue of Infectious Disease Clinics - E-Book
  • Author : Keith S. Kaye
  • Publisher : Elsevier Health Sciences
  • Release Date : 2011-03-16
  • Category: Medical
  • Pages : 312
  • ISBN Code: 1455709344

Summary: Over the past several decades, “infection control has become a rapidly growing multidisciplinary field of incredible importance with regard to the safety of patients and healthcare workers, regulation and accreditation of healthcare facilities, and finances. The focus of this field has increasingly turned to prevention rather than control of hospital-acquired infections. This issue will bring the infectious disease specialist up to date on important topics such as hand hygiene, sterilization, methicillin-resistant Staphylococcus aureus, antibiotic stewardship, and specific infections of particular concern.

The Resistance Phenomenon in Microbes and Infectious Disease Vectors
  • Author : Institute of Medicine,Board on Global Health,Forum on Emerging Infections
  • Publisher : National Academies Press
  • Release Date : 2003-03-26
  • Category: Medical
  • Pages : 333
  • ISBN Code: 9780309168304

Summary: The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

Antibiotics and Bacterial Resistance
  • Author : Wiley
  • Publisher : John Wiley & Sons
  • Release Date : 2013-01-14
  • Category: Medical
  • Pages : 146
  • ISBN Code: 1118580915

Summary: The need for novel antibiotics is greater now than perhaps anytime since the pre-antibiotic era. Indeed, the recent collapse ofmany pharmaceutical antibacterial groups, combined with theemergence of hypervirulent and pan-antibiotic-resistant bacteriahas severely compromised infection treatment options and led todramatic increases in the incidence and severity of bacterialinfections. This collection of reviews and laboratory protocols gives thereader an introduction to the causes of antibiotic resistance, thebacterial strains that pose the largest danger to humans (i.e.,streptococci, pneumococci and enterococci) and the antimicrobialagents used to combat infections with these organisms. Some newavenues that are being investigated for antibiotic development arealso discussed. Such developments include the discovery of agentsthat inhibit bacterial RNA degradation, the bacterial ribosome, andstructure-based approaches to antibiotic drug discovery. Two laboratory protocols are provided to illustrate differentstrategies for discovering new antibiotics. One is a bacterialgrowth inhibition assay to identify inhibitors of bacterial growththat specifically target conditionally essential enzymes in thepathway of interest. The other protocol is used to identifyinhibitors of bacterial cell-to-cell signaling. This e-book — a curated collection from eLS, WIREs, andCurrent Protocols — offers a fantastic introduction to thefield of antibiotics and antibiotic resistance for students orinterdisciplinary collaborators. Table of Contents: Introduction Antibiotics and the Evolution of Antibiotic Resistance eLS Jose L Martinez, Fernando Baquero Antimicrobials Against Streptococci, Pneumococci andEnterococci eLS Susan Donabedian, Adenike Shoyinka Techniques & Applications RNA decay: a novel therapeutic target in bacteria WIREs RNA Tess M. Eidem, Christelle M. Roux, Paul M. Dunman Antibiotics that target protein synthesis WIREs RNA Lisa S. McCoy, Yun Xie, Yitzhak Tor Methods High-Throughput Assessment of Bacterial Growth Inhibition byOptical Density Measurements Current Protocols Chemical Biology Jennifer Campbell Structure-Based Approaches to Antibiotic Drug Discovery Current Protocols Microbiology George Nicola, Ruben Abagyan Novel Approaches to Bacterial Infection Therapy by Interferingwith Cell-to-Cell Signaling Current Protocols Microbiology David A. Rasko, Vanessa Sperandio

The New Profile of Drug-Resistant Tuberculosis in Russia
  • Author : Russian Academy of Medical Sciences,Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation
  • Publisher : National Academies Press
  • Release Date : 2011-08-07
  • Category: Medical
  • Pages : 158
  • ISBN Code: 0309162971

Summary: An estimated 2 billion people, one third of the global population, are infected with Mycobacterium tuberculosis, the bacterium that causes tuberculosis. Spread through the air, this infectious disease killed 1.7 million in 2009, and is the leading killer of people with HIV. Tuberculosis (TB) is also a disease of poverty--the vast majority of tuberculosis deaths occur in the developing world. Exacerbating the devastation caused by TB is the growing threat of drug-resistant forms of the disease in many parts of the world. Drug-resistant tuberculosis presents a number of significant challenges in terms of controlling its spread, diagnosing patients quickly and accurately, and using drugs to treat patients effectively. In Russia in recent decades, the rise of these strains of TB, resistant to standard antibiotic treatment, has been exacerbated by the occurrence of social, political, and economic upheavals. The Institute of Medicine (IOM) Forum on Drug Discovery, Development, and Translation, in conjunction with the Russian Academy of Medical Sciences held a workshop to discuss ways to fight the growing threat of drug-resistant TB. The New Profile of Drug-Resistant Tuberculosis in Russia: A Global and Local Perspective: Summary of a Joint Workshop presents information from experts on the nature of this threat and how it can be addressed by exploring various treatment and diagnostic options.

Ethics and Drug Resistance: Collective Responsibility for Global Public Health
  • Author : Euzebiusz Jamrozik,Michael Selgelid
  • Publisher : Springer Nature
  • Release Date : 2020-10-26
  • Category: Philosophy
  • Pages : 448
  • ISBN Code: 3030278743

Summary: This Open Access volume provides in-depth analysis of the wide range of ethical issues associated with drug-resistant infectious diseases. Antimicrobial resistance (AMR) is widely recognized to be one of the greatest threats to global public health in coming decades; and it has thus become a major topic of discussion among leading bioethicists and scholars from related disciplines including economics, epidemiology, law, and political theory. Topics covered in this volume include responsible use of antimicrobials; control of multi-resistant hospital-acquired infections; privacy and data collection; antibiotic use in childhood and at the end of life; agricultural and veterinary sources of resistance; resistant HIV, tuberculosis, and malaria; mandatory treatment; and trade-offs between current and future generations. As the first book focused on ethical issues associated with drug resistance, it makes a timely contribution to debates regarding practice and policy that are of crucial importance to global public health in the 21st century.

Antibiotic and Chemotherapy E-Book
  • Author : Roger G. Finch,David Greenwood,Richard J. Whitley,S. Ragnar Norrby
  • Publisher : Elsevier Health Sciences
  • Release Date : 2010-11-30
  • Category: Medical
  • Pages : 916
  • ISBN Code: 0702047651

Summary: Well-respected and widely regarded as the most comprehensive text in the field, Antibiotic and Chemotherapy, 9th Edition by Drs. Finch, Greenwood, Whitley, and Norrby, provides globally relevant coverage of all types of antimicrobial agents used in human medicine, including all antiviral, antiprotozoan and anthelminthic agents. Comprehensively updated to include new FDA and EMEA regulations, this edition keeps you current with brand-new information about antiretroviral agents and HIV, superficial and mucocutaneous myscoses and systemic infections, management of the immunocompromised patient, treatment of antimicrobial resistance, plus coverage of new anti-sepsis agents and host/microbe modulators. Reference is easy thanks to a unique 3-part structure covering general aspects of treatment; reviews of every agent; and details of treatments of particular infections. Offer the best possible care and information to your patients about the increasing problem of multi-drug resistance and the wide range of new antiviral therapies now available for the treatment of HIV and other viral infections. Stay current with 21 new chapters including the latest information on superficial and mucocutaneous mycoses, systemic infections, anti-retroviral agents, and HIV. Get fresh perspectives and insights thanks to 21 newly-authored and extensively re-written chapters. Easily access information thanks to a unique 3-part structure covering general aspects of treatment; reviews of every agent; and details of treatments of particular infections. Apply the latest treatments for anti-microbial organisms such as MRSA, and multi-drug resistant forms of TB, malaria and gonorrhea. Keep up on the latest FDA and EMEA regulations.

Antimicrobial Resistance and Food Safety
  • Author : Chin-Yi Chen,Xianghe Yan,Charlene R. Jackson
  • Publisher : Academic Press
  • Release Date : 2015-04-21
  • Category: Science
  • Pages : 452
  • ISBN Code: 9780128012147

Summary: Antimicrobial Resistance and Food Safety: Methods and Techniques introduces antimicrobial resistant food-borne pathogens, their surveillance and epidemiology, emerging resistance and resistant pathogens. This analysis is followed by a systematic presentation of currently applied methodology and technology, including advanced technologies for detection, intervention, and information technologies. This reference can be used as a practical guide for scientists, food engineers, and regulatory personnel as well as students in food safety, food microbiology, or food science. Includes analysis of all major pathogens of concern Provides many case studies and examples of fundamental research findings Presents recent advances in methodologies and analytical software Demonstrates risk assessment using information technologies in foodborne pathogens

An Overview of Tropical Diseases
  • Author : Amidou Samie
  • Publisher : BoD – Books on Demand
  • Release Date : 2015-12-02
  • Category: Medical
  • Pages : 212
  • ISBN Code: 953512224X

Summary: Tropical diseases affect millions of people throughout the world and particularly in the developing countries. The millennium development goals had specifically targeted HIV/AIDS and Malaria for substantial reduction as well as Tuberculosis while many other tropical diseases have been neglected. The new sustainable development goals have not made such distinction and have targeted all diseases for elimination for the improvement of the quality of life of human beings on earth. The present book was developed to provide an update on issues relevant to the treatment of selected tropical diseases such as tuberculosis, malaria, leishmaniasis, schistosomiasis and ectoparasites such as chiggers which are widely distributed throughout the world. The control of these infections has been hampered by the development of drug resistance and the lack of the development of new and more effective drugs. The understanding of the biochemical processes underlying drug activity is therefore essential for the potential elimination of these infections.

Infection Prevention and Control at a Glance
  • Author : Debbie Weston,Alison Burgess,Sue Roberts
  • Publisher : John Wiley & Sons
  • Release Date : 2016-11-30
  • Category: Medical
  • Pages : 144
  • ISBN Code: 1118973550

Summary: Infection Prevention and Control at a Glance is the perfect companion for study and revision for pre-registration nursing and healthcare students, as well as qualified nurses and medical students. Infection prevention and control is one of the key five ‘essential skills clusters’ that is incorporated into all pre-registration nursing programmes. This highly visual and dynamic book is a thorough resource for nurses wanting to consolidate and expand their knowledge of this important part of nursing. Written by experienced infection prevention and control specialist nurses, it provides a concise and simple approach to a vast and complex subject, and equips the reader with key information in relation to various aspects of infection prevention and control practice. Provides a snap-shot of the application of infection prevention and control in practice and the key infections affecting patients in both acute and primary care A uniquely visual and accessible overview of a topic of relevance to all nursing staff Includes key points for clinical practice, patient management, and signposting of key national guidance documents and websites Available in a wide-range of digital formats - perfect for 'on the go' study and revision

The Microbe-Host Interface in Respiratory Tract Infections
  • Author : Jan L. L. Kimpen,Octavio Ramilo
  • Publisher : CRC Press
  • Release Date : 2004-12-22
  • Category: Science
  • Pages : 324
  • ISBN Code: 9780849336461

Summary: The molecular pathogenesis of microbial agents responsible for respiratory tract infections (RTIs) has been the focus of much research in recent years. The emphasis has been on developing new treatments such as novel antimicrobials and more effective vaccines. Significant attention has also been paid to improving molecular diagnostic methods to identify RTI-causing microbes, as well as understanding the host response to them. The Microbe-Host Interface in Respiratory Tract Infections presents an overview of the current knowledge in this area. It provides us with the first coherent picture of emerging strategies for controlling the microbes responsible for RTIs. This comprehensive volume is divided into three sections: the first reviews topics of general interest; the second focuses on bacterial and atypical RTIs; while the final section covers viral RTIs. Each of the chapters is the work of two or more of the top scientists in the field writing about their own pioneering research. Various chapters comment on vaccines, antibiotics, and molecular diagnostic methods. This cutting-edge work is essential reading for research microbiologists and other scientists involved in the investigation and treatment of RTIs.

Functionalized Nanomaterials for the Management of Microbial Infection
  • Author : Rabah Boukherroub,Sabine Szunerits,Djamel Drider
  • Publisher : Elsevier
  • Release Date : 2017-01-03
  • Category:
  • Pages : 338
  • ISBN Code: 9780323416252

Summary: Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens. The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle. Provides the information users need to integrate antibacterial nanoparticles into future treatments Gives readers with backgrounds in nanotechnology, chemistry, and materials science an understanding of the main issues concerning microbial drug resistance and its challenges Includes real-life case studies that illustrates how functionalized nanomaterials are used to manage microbial infection